The intensity of free radical processes and chaperone activity in the saliva of patients with type 2 diabetes

Introduction: Saliva is a clinically informative biological fluid that contains many biomarkers, allowing multiple analyses to be performed. Aim: The objectives of this study were the assessment serum and saliva levels biochemical parameters intensity free radical processes in T2DM patients identification correlation between certain criteria. Methods: This case-control included 40 patients, which compared with healthy individuals. glucose, cholesterol triglycerides, total protein, diene conjugates, chaperone activity measured using spectrophotometric method. concentration 8-oxo-2'-deoxyguanosine was assessed by competitive enzyme-linked immunosorbent assay. Results: It established progression diabetes led an increase glucose saliva. content conjugated dienes increased associated level glycated hemoglobin. protein control. analysis revealed relationship Conclusions: According results analysis, pathological changes DM affected salivary glands their secretions. obtained allowed us recommend as alternative blood for diagnosis monitoring treatments since it readily available quickly responds metabolism body.